CALL FOR PAPERS Mitochondria in Cardiovascular Physiology and Disease Redox regulation of insulin sensitivity due to enhanced fatty acid utilization in the mitochondria
نویسندگان
چکیده
Paul M. Rindler, Clair L. Crewe, Jolyn Fernandes, Michael Kinter, and Luke I. Szweda Free Radical Biology and Aging Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma; Department of Biochemistry and Molecular Biology, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma; and Department of Geriatric Medicine, Reynolds Center on Aging, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma
منابع مشابه
Redox regulation of insulin sensitivity due to enhanced fatty acid utilization in the mitochondria.
Obesity enhances the risk for the development of type 2 diabetes and cardiovascular disease. Loss in insulin sensitivity and diminished ability of muscle to take up and use glucose are characteristics of type 2 diabetes. Paradoxically, regulatory mechanisms that promote utilization of fatty acids appear to initiate diet-induced insulin insensitivity. In this review, we discuss recent findings i...
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